Best Netrunner Build - 10K+ Combo Damage - Cyberpunk 2077

Netrunner Build - 10K Combo Damage

I enjoyed making this build and it required a lot of testing. Many things changed in the recent big update specifically, the RAM economy and how quickhacks should be used. Many of the players found it difficult to play in this class, but I am here to help.

You will mostly use quickhacks to disable, and damage enemies. This requires certain steps to make so that the build can pull off the infamous Infinite Overclock combo. There are many other quickhack combos, but this is the most powerful one, where you use your HP to fuel quickhack uploads.

If the situation arises that you don't have RAM, fear not. There is a perfect alternative for this - smart weapons. They can be very powerful, especially if used together with quickhacks. Moreover, they make combat somewhat easier, as you only need to hold the trigger, everything else is done by an automatic targeting system.

Unfortunately, I will not be going into Monowire cyberware. I have a Monowire Build ready, however, for this one I chose not to. The main reason is that the build uses Smart Weapons which play a similar role.

Attributes

First, let's go through attributes, they will decide the direction of the build and give access to different tiers of perks. The higher tier gives better actions and passives to further support the build. Let's take a look at what we need for the Netrunner Build.

Starting Game

Here are what attributes you should be taking at the start of the game. I also recommend checking my Beginner Tips Guide, to learn more information about Cyberpunk 2077, if you are just starting

Attribute	Allocation	Description
Intelligence	+3	The main attribute of Netrunner is to ensure additional RAM capacity. This will further unlock new perks.
Body	+3	Gives bonus HP and first-tier perks
Technical Ability	+1	Starting progression to get first-tier perks.

End Game Attributes

Here is the goal of Netrunner Build.

Attribute	Total Allocation	Description
Reflexes	9	The perk tree is only relevant for mobility perks, specifically for weapon handling and Dash.
Body	15	You need one main perk from this attribute, that will give a huge survivability boost when using Overclock​
Technical Ability	20	It will provide some survivability perks and additional cyberware capacity as it is very important for this build.
Cool	17	Cool is mainly here to optimize the quickhack damage in the late game. It serves minimal purpose before that even if you are doing a stealth run.
Intelligence	20	High intelligence will unlock all the perks in the tree, increase total RAM, and give decent bonuses from some cyberware.

Perks

Let's go through the perks of the Netrunner Build. We will go through about 65~ perk points for the build, and the game awards about 80. So you will have perk points left to adjust the build to your needs.

Intelligence Perks

The main perk tree of Netrunner build. Unlocks a lot of useful actions and combos to make everything work together with quickhacks. I did not take all the perks as I was constrained by them. However, by reaching level 60, you could pick most of them, especially smart weapon ones.

Level 4 Perks

Perk	Description
Eye in the Sky​	Nothing special, I did not use cameras, but it is needed for progression. It could be great for initiating combat from stealth early in the game.
Warning: Explosion Hazard​	Very valuable perk, that makes exploding containers deal more damage. This is probably the easiest damage source in the game requiring only 2 RAM.
Optimization​	The recovery rate is good, but we are interested in progressing further and unlocking new perks.
Encryption​	Somewhat good perk, as you are killing enemies left and right, this can ensure that you don't even enter the combat before everyone is cleared.
Subordination​ (Optional)	I found this useful on some stronger enemies like MaxTac. Optional if you find that the duration increase is unnecessary

Level 9 Perks

Perk	Description
Embedded Exploit	To fully utilize the damage potential, be sure to first upload something like Ping, Cyberware Malfunction, or Sonic Shock. This will easily boost your damage, I recommend this combo against elite foes.
ICEpick	Some bonus RAM savings when mixing quickhacks.
System Overwhelm​	Further improves damage by unique quickhack effects. With increased queue size this will be a worthwhile combo.
Speculation	We are more interested in unlocking the next perk in the line. This is just a good source of RAM to have.
Recirculation	A useful perk, that will help with RAM management. In case you are stranded, just use your Smart Gun, to fill up your cyberdeck.
Acquisition Specialist​	Improves smart weapons by increasing lock-on speed and reticle size.
Precision Subroutines​	Increases accuracy, but we are mainly interested in the next perk it unlocks.
Hack Queue	Allows the creation of some sweet combos and utilizes unique effects with the next perks.
Data Recycler	With Overclock and Blood Daemon, this perk will allow us to obtain RAM from health
Feedback Loop​	I would say this is not a crucial perk if you have Overclock. However, if you have a free perk point you can invest into it.
Counter-a-hack​	Reveals enemy netrunner positions allowing you to instantly counter them with your quickhacks.

Level 15 Perks

Perk	Description
Overclock	The ultimate perk of Lucy's build. You can sacrifice HP to obtain additional RAM. Pairing it with Hack Queue, Blood Daemon, and Burnout Synapse, allows you to sustain this effect infinitely.
Sublimation	Improves survivability and unlocks the next perk in the tree
Race Against Mind	More damage to the lower HP? This is auto-pick for the build
Power Surge​	I would say this is an optional perk in case you need more survivability.
Queue Acceleration	Further improves queue size, allowing the creation of even more powerful combos
Queue Hack_Root	Nothing special, just a small improvement to save RAM. It will also unlock the next perk.
Blood Daemon	This is a bad boy. It unlocks huge potential for Overclock allowing you to regain your lost health.
Queue Prioritization	Faster upload speed for the first Quickhack, when you fill up the queue.
Target Lock Transfer​	Further improves smart weapons, by allowing you to switch them and not losing the targeting.

Level 20 Perks

Perk	Description
Queue Mastery	Once you get this perk, be sure to always fill the queue for lockdown. I recommend using Cyberware Malfunction as it is cheap. This will result in +15% higher damage against the target.
Smart Synergy​	Instant Target Lock and more damage? Worth it if you are utilizing Smart Weapons.

So I did not take Spillover. The main reason is that some quickhacks may spread when you don't want that to happen and this takes full control out of your hands, especially when out of combat.

Body Perks

This is a very important perk tree. Although we will only take a few perks, they will play a huge role in higher survivability. First, while Overclock is active, having some survivability will ensure that the Netrunner build will not die once spending all HP on quickhacks.

Level 4 Perks

Perk	Description
Painkiller	Allows regenerating HP during combat. This is very valuable, especially in the early game, where you often may not have healing items.
Dorph-head	A brief damage reduction from mitigation for 2 seconds. Very valuable once you are in a shootout

Level 15 Perks

Perk	Description
Adrenaline Rush	Gives a huge survivability boost by unlocking a new health bar after activating a healing item. It will ensure that you don't die while using Overclock and with the next perks gives some good bonuses.
Juggernaut	Once Adrenaline Rush is up and running this will give a decent boost to all damage and faster movement speed
Calm Mind	Delay of Adrenaline Rush decaying.

Technical Ability Perks

Now the third pillar of the build ensures you can equip the best Cyberware in the game and one-shot most of the enemies.

Level 4 Perks

Perk	Description
Glutton for War	As healing items play an important role in this build, the perk ensures that you regain them faster.

Level 9 Perks

Perk	Description
All Things Cyber	Lower cyberware capacity cost for some slots and bonus stat modifier increase.
Renaissance Punk	Additional cyberware capacity based on the attributes invested.
Chrome Constitution​	Gives a flat 5% damage reduction, greatly improving the build's survivability.
Health Freak​	Unlocks third healing item. This will greatly boost the survivability of the build and allow to release of more quickhacks while in Overclock​
Borrowed Time​	Together with Biomonitor, anytime you kill an enemy close to death this will instantly restore your health.

Level 15 Perks

Perk	Description
License to Chrome	A new cyberware slot and bonus armor, moreover unlock the next perks.
Extended Warranty​	Extends the duration of cyberware effects, which is extremely useful for this build and the actions we use.
Cyborg​ (optional)	This is an optional perk, which improves Countershell and other cyberware but does not affect Overclock.
Pyromania​ (optional)	I recommend this combo if you are using Shock-n-Awe cyberware. It allows easy stacking Pyromania, which gives a bonus mitigation chance. This way you can easily reach 100%.
Heat Shield​ (optional)

Level 20 Perks

Perk	Description
Edgerunner​	And we unlock extremely powerful perks. This will ensure that we can easily fill all the cyberware slots and equip all the powerful choices.
Ticking Time Bomb​ (optional)	Activates a stack of Pyromania​ and reduces incoming damage. It can also become irritating as the effect might kill NPCs unintentionally, so keep that in mind.

Reflexes Perks

The attribute tree mainly plays a role in enabling better mobility. There are some useful weapon perks, but those are relevant only if taking SMGs or Assault Rifles.

Level 4 Perks

Perk	Description
Slippery	Mainly take this for progression, but as long as you move, the benefits of the perk will pay off.
Muscle Memory​	Allows reloading while running, making the combat somewhat easier, especially early on, when you don't have good quickhacks.

Level 9 Perks

Perk	Description
Dash	The main perk that improves the mobility of Lucy's build.
Can't Touch This​	A huge survivability boost for 2 seconds after using a healing item. We will be popping them left and right once Overclock​ is active.

Perks - Relic

These perks are available with Phantom Liberty DLC. They will give further improvements to some of the game mechanics. To be honest, there are not many contenders for this specific Netrunner Build.

Priority	Perk	Description
1	Vulnerability Analytics	Shows vulnerabilities, that allow for huge damage boosts. Good synergy with Smart Weapons as they will automatically target these parts
2	Machine Learning	Increases the frequency of vulnerabilities.

If you wish to use Monowire then Jailbreak​ and Data Tunneling​ are perfect choices. However, I did not use these for the build. 

Equipment for Netrunner

Now let's take a look at what gear the netrunner can benefit from. I would generally recommend Smart weapons as you take relevant perks and they are fairly effective. Moreover, kills made with them will restore RAM.

In the late game, you will most likely don't even use these weapons as quickhacks will destroy any foe with just one upload. You will need them on more difficult encounters like bosses or even Cyberpsychos.

Smart Pistols

In my opinion, these weapons are good to have on hand, however, they pale in comparison to SMGs and other smart weapons.

Item	Description
Genjiroh	I think the most effective smart pistol. Deals a decent amount of damage, can apply shock, and targets multiple targets at the same time.
Crimestopper	Has a very fast attack speed, and can immobilize targets by uploading cripple movement quickhack. Very enjoyable weapon to use.
Ogou	Releases two explosive rounds, and gets bonuses to armor penetration and critical damage.

Smart SMGs

The most fun weapons to use for Netrunner build. They have extremely high rates of fire and some of them come with strong unique effects

Item	Description
Yinglong	Very fun weapon to use due to its extremely high rate of fire. Pop Reboot Optics or Overheat for even more damage. That is not all, it also has a chance to deal shock damage and release small EMPs.
Pizdets	Iconic SMG that has a built-in silencer. A perfect option if you want to do some quiet snipes. The downside is its low magazine size
Warden	The normal version of the newly introduced SMG. Has a big magazine size, and with some mods, it can rival even iconic versions. The perfect option to continuously spray foes
Prototype: Shingen Mark V	Releases explosive rounds and has a decent burn chance. It can be used with Contagion quickhack to create more explosions. The only downside is that it has a burst-fire mode, instead of automatic.

Smart Assault Rifles

Unfortunately, there are only two options to choose from here. Another downside is that their damage is not as high as SMGs.

Item	Description
Hercules 3AX	The coolest-looking smart weapon? I think yes. Give it a try if you have a chance. It can also poison enemies.
Divided We Stand	A decent assault rifle that can easily hit multiple enemies and has increased damage.

Smart Sniper Rifles

Item	Description
Yasha	If you managed to land your hands on this one, definitely get it. Gives an additional modification slot.
Ashura	A very powerful weapon. Unfortunately, it only has 1 ammo per magazine. So make that one shot count. Also, make sure to upload a quickhack to the enemy before shooting.

Smart Shotguns

In my personal opinion, these weapons are somewhat disappointing. They are of course powerful, but either they are weaker or limited by their fire rate.

Item	Description
DB-4 Palica	Unfortunately, this does not have an iconic version. Somewhat fun shotgun to use, that releases multiple homing rockets to reach its target
Ba Xing Chong	Crazy shotgun that releases multiple exploding pellets, destroying anything in its path. The main downside is that after each shot you will have to reload.

Cyberware

Cyberware is a unique mechanic that allows you to fill cyberware slots with implants. Early games can be quite difficult as you will have limited capacity. However, as you progress and drop more Capacity Shards, you will be able to equip more.

First Priority Cyberware

This is what is essential to make the build work. I would even recommend dropping everything else to equip these if cyberware capacity doesn't allow it. These cyberware selections make the core of the build.

Slot	Cyberware	Description
Frontal Cortex 1	COX-2 Cybersomatic Optimizer	The single most powerful cyberware for netrunner. Makes all quickhacks do guaranteed critical hits. After you obtain this one, most of the enemies will be one shot with the correct quickhack sequence
	Bioconductor	A weaker version, if you do not have access to the one above or are limited by cyberware capacity. I would only equip this after level 30+.
	RAM Upgrade	A cheaper cyberware option, that is perfect until level 30. After that, you will have RAM capacity to use the above ones.
Frontal Cortex 2	EX-Disk	Gives a flat increase in Total RAM.
Skeleton 1	Spring Joints	Improves mitigation strength, complementing  Countershell, and Neofiber.
Nervous System 1	Neofiber	It gives a higher mitigation chance which makes it harder for enemies to detect you and increases your survivability.
Integumentary System 1	Countershell	Very cheap and effective cyberware that can boost mitigation chance by 50%.
Operating System 1	Tetratronic Rippler	The best cyberdeck for pure damage with quickhacks like Short Circuit and Burnout Synapse.
	Netwatch Netdriver Mk.1	I recommend this one if you would like to upload quickhacks via devices like Cameras.
	Militech Paraline	I recommend this one if you are heavily using Smart Weapons as it will boost their damage during Overclock.
Face 1	Kiroshi "Sentry" Optics	A more relevant eye cyberware that gives bonus damage based on intelligence. Of course, this comes with higher cyberware costs.
	Basic Kiroshi Optics	Simple eye cyberware, that I think does the job for this build.
Hands 1	Smart Link	Allows Smart Weapon targeting.
Circulatory System 1	Biomonitor	Automatically heals, makes the combat somewhat easier, as you do not have to worry how long it takes to use a healing item.
Circulatory System 2	Blood Pump	The most powerful healing item in the game, it will ensure that you don't die while using Overclock.
	Heal-On-Kill	Another option that gives HP restoration on kill. This is a cheaper alternative that some people prefer.
Legs	Reinforced Tendons	My personal favorite makes traversing much easier.
	Fortified Ankles	Gives the highest jumps and high boost to armor compared to cyberware capacity cost. But you need to hold the jump button.

Second Priority Cyberware

Slot	Cyberware	Description
Frontal Cortex 2	Axolotl	This cyberware will take the build to the ultimate level. It has a very steep cyberware capacity cost. But it gives cooldown reductions for everything - Overclock, Kerenzikov, etc.
	Newton Module	Gives a cyberware cooldown reduction after taking out an enemy. It is not much, however, with multiple kills, the effect adds up.
Skeleton 2	Epimorphic Skeleton	Gives a huge armor and health boost, greatly improving survivability.
Nervous System 2	Revulsor	Improved version of Reflex Tuner, which works similarly to Sandevistan and does not slow you down
	Reflex Tuner	Excellent cyberware that kicks in when your health drops below 25%. This has a good synergy with Borrowed Time, which gives a chance to gain a health item when on Low HP.
Integumentary System 2	Shock-N-Awe	This is very powerful cyberware that gives decent armor, but most importantly it can damage surrounding foes. If prefer a playstyle where you engage in close to medium-range combat, I would recommend this cyberware. Be sure to get Pyromania​ + Heat Shield​ for the highest mitigation chance.
	Painducer	A defensive cyberware that will reduce some big damage you receive and spread it over time. Use it if you prefer staying in long range.
	Subdermal Armor	A simple cyberware that has a high armor-to-cyberware capacity cost ratio.
Integumentary System 3	Cogito Lattice	Defensive cyberware that has a very low cost. By using Overclock​ you should have very high armor.

Final Cyberware setup

The final setup gives general improvements to health regeneration and damage setup.

Slot	Cyberware	Description
Arms	Any Cyberware	Feel free to add any cyberware if you will be using Cyborg​ perk.
Skeleton 3	Kinetic Frame	As you should be maintaining high stamina, the mitigation chance will be active most of the time.
	Bionic Joints	Gives bonus armor for higher survivability.
Nervous System 3	Deep-Field Visual Interface	Gives bonus critical damage from attunement based on the Cool attribute.
	Synaptic Accelerator	Just a protectory cyberware that will give you some additional time to deal with enemies if you are detected.
Circulatory System 3	Second Heart	Although quite expensive, this ensures that you can resurrect. Together with Axolotl, this can have its cooldown reduced very fast.
	Heal-On-Kill	I would say this is the safest option, it gives an additional layer of HP restoration.

How to Use the Build

Now let's go deeper into how to effectively use the build for Netrunning. There are a lot of aspects and the build is quite complex.

Core Mechanics

So these are core mechanics that you should know to play the build effectively.

Activating Overclock

The core talent of any build that uses quickhacks is Overclock​. It enables you to use HP for quickhacks, and greatly expands the netrunning capabilities. This does seem risky and poses a few challenges. First, we need to address the limited HP:

• Adrenaline Rush​ - gives a separate layer of HP that protects you
• Blood Pump - improves healing item effectiveness
• Biomonitor - automatically uses healing item
• Heal-On-Kill - restores HP on kill
• Health Freak​ - gives another healing item

With these, you should be able to maintain the HP pool and constantly use quickhacks while in Overclock​ mode. So with various upgrades you will be able to restore HP and continue using multiple quickhacks to eliminate foes

Quickhack Order while Scanning

One of the most irritating things when playing a Netrunner is when an important quickhack is either at the end or in the middle of the list while scanning. This is a major limitation of cyberdecks, which have negative gameplay experiences.

Well, there is a way to control them which is very unintuitive, but still gives what you want. When adding quickhacks the order in which they will be shown is right bottom to right top and then left bottom to left top.

The difficulty is that when adding quickhacks, they will first be added to the end of the list, meaning you have to plan how your quickhack list will look.

So even though this system is very unintuitive at least there is a way to control it. In the image above, the quickhack list will be:

1. Cyberware Malfunction
2. Burnout Synapse
3. Short Circuit
4. Reboot Optics
5. Overheat
6. etc.

Use Smart Weapons while out of RAM

Once the RAM runs out you can either hide or use your weapon. The good thing is that with the Recirculation​ perk, each killed enemy using SMart Weapons will restore 2 RAM. Moreover, the build includes other relevant Smart Weapon perks like Acquisition Specialist​ and Target Lock Transfer.

Another option is getting the Siphon​ perk and using Monowire. But in my opinion, this is a riskier approach as you will be under enemy fire which can result in death.

Utilize Tracing to your advantage

Tracing is a stealth netrunning mechanic. Once you upload the first quickhack a bar will appear that fills up as time goes by. This means that enemies are looking for you but not yet engaged in active combat.

The mechanic creates some tensions, which may hinder the stealth playstyle. For this reason, I recommend Encryption. What you can do is try to delay entering combat as much as possible until tracing reaches 100%.

However, there are tricks on how to avoid this together and I cover it more in the Quickhack Combo guide.

Obtaining new Quickhacks

The main question is how to get new Quickhacks. Well, there are a few main ways, which are fairly simple:

• Purchase from Netrunner vendors throughout the Night City. New quickhack tiers become available as you level up. if you do not find the one you need, just rest for 24 hours, so that their inventory will reset. Quickhacks that you have will not appear in their inventory.
• Hack access points. These can be found near groups of enemies with NCPD scanners. Just use Ping which will reveal everything in the network. Generally, access points are highlighted with red color on the minimap.

Recommended Quickhacks

Item	Description
Cyberware Malfunction	This is a mandatory quickhack. First, it disables enemy cyberware and increases damage against them. Second, after you gain Embedded Exploit this ensures that by default you deal 60% more damage with subsequent quickhacks. So this should be your starting option.
Burnout Synapse	This is mandatory if you want an "advanced" netrunner build that can use quickhacks without RAM limitations, I covered it in the Quickhack combo section on how you can do it
Ping	This can be a good quickhack early in the game. It reveals enemy positions connected to the network. However, later on, this might not be as useful. You will be able to guess enemy positions and outright destroy any new foes.
Reboot Optics	Decreases enemy accuracy with weapons and increases headshot damage against them with weapons. Take this if you are using Smart Weapons.
Sonic Shock	With this Quikchack you can make an enemy disappear from the network, making them an easy picking without raising alarms. This requires at least tier 4. However, quickhacks which are used after it activates initiate Tracing. (this worked differently before patch 2.1)
Contagion	By itself, it is not a very powerful quickhack. Its main appeal is that from Tier 4 it can be combined with Burn effects to create explosions. Moreover, as it spreads, explosions can be created multiple times.
Overheat	Great quickhack if you are using Smart Weapons as it decreases armor and provides bonus damage. Moreover, can be used together with Contagion to create explosions.
Detonate Grenade	It is an ultimate quickhack so you may not get access to it early. However, once you get it you can use it very cheaply after creating explosions.
Memory Wipe	The new king of stealth netrunning. Memory Wipe allows for avoiding Tracing. You will need Tier 4 for this. Higher tiers are very expensive in terms of RAM.
Short Circuit	A very powerful quickhack that deals electrical damage. It is very effective against robots, drones, mechs, etc.

Quickhack combos

There were big changes to quickhacks after the big Cyberpunk 2.0 update, now they have a synergy with each other. Overall, their costs have been increased, and you will mostly be able to use 3-4 quickhacks, without Overclock.

When fighting a group of elites this will be not enough, so you have to be smart about it. I recommend reading the Quickhack Combo guide as it goes into depth on how best to utilize these new mechanics. I recommend a few combos in the next sections where I talk about Early and late-game combat.

Early Game Combat

The early game of netrunner tactics and quickhacks that you should use. I also recommend checking the Beginner Tips Guide which is perfect for starting players to learn more about game mechanics and easily missable things.

The Early Game problems

Unfortunately, early games with Netrunner build, especially on Very Hard can be brutal. First, are not able to use high-tier quickhacks. Second, low RAM and limited netrunning capabilities allow only a few quickhack uploads, while you have to wait for the recovery.

For this reason, I recommend using or carrying a pistol, to make the early level easier. Also, don't forget about grenades. You will be getting better and better and it starts becoming easier from level 15. Do not let this deter you as you can see from the showcases, the build is a beast in later levels.

Gun combat

In case you enter Gun Combat and want to maximize the effectiveness there are a lot of options. I would like to cover one of the simplest and most effective.

First, be sure to have a smart weapon, they target enemy weak spots and have a good synergy with some cyberdecks. Now, for quickhacks, I recommend using:

Item	Description
Cyberware Malfunction	One of the cheapest quickhacks. Disables enemy cyberware increases damage against them, and stacks for stronger effects.
Overheat	Starts burning the enemy, but the most important effect is that it melts their armor and each shot against them gets bonus fire damage.
Reboot Optics	Makes the enemy almost blind, making it easier to approach them and their shots miss. Moreover, you deal bonus headshot damage.

You can use all of them together against strong enemies like cyberpsychos, easily destroying them in a matter of seconds with a weapon like Yinglong.

Creating Explosions

Explosions are a good source of area of effect damage, that deal decent damage and can be very cheap to use. The easiest source is red containers found in the environment. You can either explode them with quickhacks or weapons. Be sure to have Warning: Explosion Hazard to increase the damage of environment detonations.

Short Circuit against normal targets

This combo is as simple as it gets and is a good option for taking out normal enemies mostly with one HP bar. For this, you will need two quickhacks - a Short Circuit and Cyberware Malfunction. This will activate three effects:

1. Embedded Exploit​
2. Bonus damage from Cyberware Malfunction
3. Additional combo bonus from Short Circuit itself

Sequence	Action	Description
1	Cyberware Malfunction	Use it one or two times to weaken the enemy.
2	Short Circuit	Short Circuit will create a combo and deal additional damage. Moreover, this will also activate Embedded Exploit​

It's a very simple combo but falls short once you start fighting stronger enemies like elites.

Reboot Optics to weaken enemies

Early in the game, you will find yourself in situations where you are stranded with a minimal amount of RAM and under heavy fire from enemies. Moreover, it might get worse if something like a buffed-up melee foe appears near you.

For this reason, I recommend using Reboot Optics. It is very cheap, makes enemies miss you or outright not detect you and with higher tiers, you deal more damage and restore RAM.

Simple Burnout Synapse

Using Burnout Synapse after Covert or any other non-combat quickhack will allow it to deal substantial damage. This is the earliest combo you can do, at level 20 that will be able to take some of the grunts with a single upload.

For this to work effectively you will need Embedded Exploit​ and Hack Queue​ as quality of life improvement. This combo is important as once you get access to better cyberware and higher-tier quickhacks it will be your bread and butter. It is called - the Infinite Overclock combo, which I cover in the next section.

Late Game Combat

Now for the late game, there is a wide array of options. Again I urge checking Quickhack Combo Guide to find all the options to maximize Netrunner potential.

Burnout Synapse with Infinite Overclock

This is the most powerful combo that you can use to more or less never run out of RAM. For now, this looks to be the top combination of quickhacking since the 2.0 update. So what makes it powerful? Well, this is a combination of multiple perks and quickhacks. Let's go step by step

1. Overclock allows to use HP instead of RAM for quickhacks
2. Hack Queue and Queue Acceleration allow uploading multiple quickhacks in succession
3. Data Recycler returns 80% of RAM that has been used, so we are trading HP for RAM
4. Finally, Blood Daemon restores HP based on quickhacks in the queue, which we can be further used to fuel Overclock

This is just the part of it. The core of this combo is Burnout Synapse. It has unique effects, if you kill an enemy using it, the Overclock duration is extended by 5 seconds. As long as there are enemies you should be able to sustain it and use HP for Quickhack uploads.

So here are  recommended sequences based on the situation:

Most damage

Be sure to activate Overclock​ as this gives a huge damage boost.

Sequence	Action	Description
1	Cyberware Malfunction	This activates Embedded Exploit​ and Tetratronic Rippler's unique effects. Moreover, Cyberware Malfunction increases overall damage and disables cyberware. The big costing quickhacks are there to activate the bonus effect from Burnout Synapse.
2	Burnout Synapse
3	Cyberware Malfunction
4	Ultimate Quickhack with high RAM cost

Best when high-level in normal encounters

Sequence	Action	Description
1	Burnout Synapse	Once you get some good cyberware and can one-shot most of the enemies, using this one will net you the best results. You can recoup 75 HP from Blood Daemon (thanks to 3x Cyberware Malfunction), at the cost of less damage, as now Embedded Exploit​ will not activate. But this is perfect for simple enemies or in late-game normal encounters.
2	Cyberware Malfunction
3	Cyberware Malfunction
4	Cyberware Malfunction

Stealth Netrunning setup

Stealth Netrunning is also a viable option. With quickhacks like Memory Wipe, you can eliminate the Tracing mechanic and follow up with any hack. This is not available early in the game, so here are some things that you can do.

First, in the early game make sure you have Encryption, this will somewhat delay until you are detected. Shadowrunner​ is another great addition, but it requires you to do a takedown (run behind an enemy and grab them). This is risky and may not be the preferred choice.

Now at level 30, you will unlock Epic quickhacks. This is when you can get Memory Wipe Tier 4. It costs 10 RAM to use and does what Sonic Shock did - disable tracing on subsequent uploads.

Ensure you disable the Spillover​ perk; otherwise, quickhacks can spread to nearby targets, who did not have Memory Wipe uploaded yet.

So if you want a stealth approach always use Memory Wipe Tier 4 first. This will most likely require you to activate Overclock​ more often. Here is the combo to take out enemies without activating tracing:

Sequence	Action	Description
1	Memory Wipe (Tier 4+)	A very simple combo, that also has low costs. Make sure that you use Memory Wipe Tier 4, and Sonic Shock Tier 5 or Iconic. This way it guarantees the lowest RAM cost. Moreover, you can take out two enemies at the same time in the endgame easily before you activate Overclock.
2	Reboot Optics
3	Sonic Shock (Tier 5+)

Wanted to thank u/Past_Bat1045 for sharing this stealth combo - https://www.reddit.com/r/cyberpunkgame/comments/18da9y2/stealth_netrunning_guide/

No Tracing with insta-kills (might be a bug)

Okay, so you can do some crazy clearing of enemies with Stealth netrunning. How this can be done? There are a few conditions you have to meet:

• You need to kill the enemy with a single traceable quickhack.
• The sequence can contain quickhacks before, but they need to be untraceable (Sonic Shock, Request Backup, Ping, etc.

This allows you to kill the enemy instantly- and the tracing does not start, making it worthwhile to stack everything you can for huge damage bonuses.

Explosions with Quickhacks

The next option is to create explosions yourself with quickhacks. There is a very easy combo - Contagion + burn source. Of course, this is a bit more costly, but the effect is usually even better as you can create multiple explosions one after another.

Sequence	Action	Description
1	Contagion	Setting up the combo, by releasing the poison from the quickhack. The quick hack will spread to other enemies creating even more confusion.
2	Overheat	As you can see there are a ton of options for how you can set off these explosions. And as the Contagion spreads, you can create a second and third, if anyone is still alive. Just be aware, that weapons and Monowire, have a "chance to burn" meaning that some of them are not as effective. For example, Monowire has a 20% chance to burn, and its slow attack speed makes it a problematic choice.
	Thermal Monowire
	Incendiary Grenade
	Errata
	Prototype: Shingen Mark V

Conclusion

Thank you for reading this post on Best Netrunner Build in Cyberpunk 2077. This is the most iconic archetype and build in the game universe. The highlight of the build is quickhack combos which ensure that you can easily upload them in succession for additional effects and damage.

Cheers!